Diagnosis of Extrapulmonary Legionellosis in Allogeneic Hematopoietic Cell Transplant Recipients by Direct 16S Ribosomal Ribonucleic Acid Sequencing and Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry

نویسندگان

  • Alexandra Franco-Garcia
  • Tilly A Varughese
  • Yeon Joo Lee
  • Genovefa Papanicolaou
  • Marc K Rosenblum
  • Travis J Hollmann
  • Guenther Koehne
  • Farid Boulad
  • N Esther Babady
  • Yi-Wei Tang
  • Susan K Seo
چکیده

Identifying extrapulmonary legionellosis is difficult due to the lack of clinical suspicion and limitations of conventional microbiologic methods. We present a case series of hematopoietic cell transplant recipients with extrapulmonary legionellosis diagnosed via molecular diagnostics: 16S ribosomal ribonucleic acid gene Sanger sequencing and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.

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عنوان ژورنال:

دوره 4  شماره 

صفحات  -

تاریخ انتشار 2017